When Chloe began to lose her memory, she found that the only person she could remember was Clark and admitted to him that she had been having to remind herself of everyone else and had been faking her feelings for weeks
Chloe showed Clark the letter and stated that she would always love him, she no longer felt that strongly. Clark admitted to Lois that he was not aware that Chloe felt that intensely back then. Clark continued to support Chloe’s upcoming marriage, agreeing to give her away at the altar and stating that she had never seemed so happy.
Although they began to have differences in their thinking, Chloe and Clark continued to work together. After Clark and Lois disappeared from the farm, Chloe retrieved the Crystal of Knowledge and risking her own health, she was able to activate the Crystal and save Clark and Kara Kent from the Phantom Zone. This event prompted Oliver Queen to point out that he thought Chloe was in over her head with regards to Clark’s alien origins payday loans Wyoming.
The Legion was willing to sacrifice Chloe’s life to defeat Brainiac, but Clark convinced them to work together to save her
Clark wanted to rebuild the Fortress of Solitude to ask Jor-El to cure her, saying that he thought his secret was destroying her life. Chloe countered that she felt like knowing his secret changed her life for the better and wouldn’t give up her role for anything. Chloe’s amnesia progressed as she lost memories of Clark as well. Chloe received an MRI for treatment, and when instructed to remember a “happy place,” all of her memories were of romantic moments with Clark. Convinced of his reasons, Clark went against her wishes and asked Jor-El to remove her Brainiac infection, along with any memories of his true origins or abilities. He gave an unconscious Chloe a heartfelt apology for going back to hiding the truth, but that it was the only way he knew to keep her safe.
Chloe’s wedding proceeded as scheduled with Clark hosting it at his farm, setting a priority to make it perfect. He revealed that he had saved the boutonniere she gave him before the Spring formal and gave it to her to put in her bouquet as “something borrowed”. As they shared a dance, she said nothing would change between them, but Clark spoke as if they were not best friends anymore. Chloe revealed that she felt a weight had been lifted from her. However, the wedding was interrupted by a mysterous murderous creature, which kidnapped Chloe.
Shortly after, Clark met the Legion of Super-Heroes and told them that Chloe was missing. They informed him that in history, Clark defeated Brainiac with the red crystal, but since it was destroyed, the only way to defeat him was to kill the human host. Clark was unwilling to allow the Legion to kill Chloe and went to the Fortress to help, where he was confronted by a possessed Chloe. Brainiac inside Chloe told Clark that he chose Chloe because he knew that Clark would never hurt her. They successfully removed Brainiac and cured Chloe, in the process, restoring her memory of Clark’s secret. Chloe had no recollection of the time in which she forgot his secret and Clark did not tell her of his decision.
When Lana Lang returned to Smallville, Clark asked Chloe if they should try to rekindle their relationship and Chloe advised him to talk to Lana. She wondered what Clark’s intentions were with regards to Lois’ feelings for him but Clark did not answer. When Clark discovered Lana’s plans to steal a power suit from Lex, he questioned why Chloe did not tell him she knew of Lana’s whereabouts. Chloe reminded him again that she keeps the confidence of all of her friends.